GenepoweRx and Onco.com collaborate to bring world-class, affordable advanced gene sequencing technology for cancer patients to India

GenepoweRx, is India’s most trusted Genetic Testing company founded by Dr. Kalyan and Dr. Hima, both American Board-certified Internal Medicine Physicians with over 10 years of training and experience in clinical genomics from prestigious Stanford and Harvard University. The company takes pride in developing India’s first comprehensive Cancer Genetic Test – OncoRx, which will help oncologists to prescribe targeted therapy drugs. OncoRx is the only genetic test powered by Artificial Intelligence (AI) algorithms using US-based Memorial Sloan Kettering Cancer Center’s Precision Oncology Knowledge Base, the only FDA-recognized database for cancer to identify gene mutations associated with solid tumors and to provide accurate recommendations specific to the Indian population.

There are significant variations in the cancer genome changes between different ethnicities. Recently, the data analysis from the world’s oldest and only FDA-approved database from Memorial Sloan Kettering cancer centre revealed that EGFR mutations are more common in Asians (56%) when compared with Caucasians (16%). GenepoweRx bio-medical-informatics team has sequenced over 100 solid tumor samples in recent months and found that there are mutations which have specific therapies and facilitated the provision of specific medications on compassionate grounds from international drug manufacturers. Many novel mutations found in our population have not been reported so far in the global database. GenepoweRx is currently working on publishing these findings and deciphering the clinical importance.

Dr. Kalyan, Founder – GenepoweRx shares, “We are proud to collaborate with Onco.com. More sequencing of tumor cells is needed. We carry a mutual goal of bringing world-class advanced testing to all our patients at an affordable cost. This partnership will provide more insights into the reasons for the rise in cancer and possibly identify new targeted therapies. Collaborations like these will help improve the masses’ cancer treatment options.”

Dr. Amit Jotwani, Co-founder and Chief Oncologist, says, “I believe collaboration is the way forward to bring meaningful advancements in the fight against cancer. Cancer Genomics testing is gaining tremendous interest due to its ability to identify the most effective targeted treatments, but at the same time, the test outcomes may not give clear results due to the complexity of different mutations that may be found. Additionally, a limited understanding of mutation patterns in Indian patients makes it difficult to develop targeted therapies. Collaboration with GenepoweRx’s AI-based platform will help us better understand cancer-causing mutations among the Indian population, which in turn would help us develop more effective and affordable drugs”.

In the era of personalized medicine, genomic testing is an indispensable tool. It will lead to informed decisions and better patient outcomes with reduced side effects.

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